(19)
(11) EP 0 589 958 A1

(12)

(43) Date of publication:
06.04.1994 Bulletin 1994/14

(21) Application number: 92911924.0

(22) Date of filing: 06.05.1992
(51) International Patent Classification (IPC): 
C12N 9/ 16( . )
C12N 15/ 09( . )
C12N 15/ 62( . )
C12R 1/ 19( . )
C12N 9/ 22( . )
C12N 15/ 113( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/US1992/003793
(87) International publication number:
WO 1992/022642 (23.12.1992 Gazette 1992/32)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 11.06.1991 US 19910712905

(71) Applicant: THE GENERAL HOSPITAL CORPORATION
Boston, MA 02114 (US)

(72) Inventors:
  • CHANG, Yie-Hwa
    Somerville, MA 02143 (US)
  • SMITH, John, A.
    Scotch Plains, NJ 07076-2422 (US)

(74) Representative: Fischer, Hans-Jürgen, Dr., et al 
Hoechst AG Patent- und Lizenzabteilung Gebäude K 801
D-65926 Frankfurt am Main
D-65926 Frankfurt am Main (DE)

   


(54) UNIVERSAL SITE-SPECIFIC NUCLEASES