(19)
(11) EP 0 590 051 A1

(12)

(43) Date of publication:
06.04.1994 Bulletin 1994/14

(21) Application number: 92914138.0

(22) Date of filing: 11.06.1992
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 39/ 395( . )
A61P 29/ 00( . )
C07K 14/ 00( . )
C07K 16/ 00( . )
C07K 16/ 28( . )
C12N 5/ 10( . )
C12N 15/ 09( . )
C12P 21/ 08( . )
G01N 33/ 53( . )
G01N 33/ 577( . )
A61K 39/ 00( . )
A61K 48/ 00( . )
A61P 37/ 00( . )
C07K 14/ 705( . )
C07K 16/ 18( . )
C07K 19/ 00( . )
C12N 15/ 00( . )
C12P 21/ 02( . )
C12Q 1/ 68( . )
G01N 33/ 569( . )
(86) International application number:
PCT/US1992/004896
(87) International publication number:
WO 1992/022323 (23.12.1992 Gazette 1992/32)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 11.06.1991 US 19910712879

(71) Applicant: CENTER FOR BLOOD RESEARCH, INC.
Boston, MA 02115 (US)

(72) Inventors:
  • DeFOUGEROLLES, Antonin, R.
    Cambridge, MA 02138 (US)
  • SPRINGER, Timothy, A.
    Chestnut Hill, MA 02167 (US)

(74) Representative: Roberts, Alison Christine 
Kilburn & Strode, 30 John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) INTERCELLULAR ADHESION MOLECULE-3 AND ITS BINDING LIGANDS