(19)
(11)
EP 0 590 059 A1
(12)
(43)
Date of publication:
06.04.1994
Bulletin 1994/14
(21)
Application number:
92914222.0
(22)
Date of filing:
11.06.1992
(51)
International Patent Classification (IPC):
C12N
15/
09
( . )
C07K
14/
475
( . )
C07K
14/
52
( . )
C12P
21/
02
( . )
C07K
14/
245
( . )
C07K
14/
48
( . )
C12N
15/
70
( . )
C12R
1/
19
( . )
(86)
International application number:
PCT/US1992/005006
(87)
International publication number:
WO 1992/022665
(
23.12.1992
Gazette 1992/32)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
(30)
Priority:
12.06.1991
US 19910715185
21.11.1991
US 19910796106
(71)
Applicant:
REGENERON PHARMACEUTICALS, INC.
Tarrytown, NY 10591-6707 (US)
(72)
Inventors:
PANAYOTATOS, Nikos
Orangeburg, NY 10962 (US)
FANDL, James, P.
La Grangeville, NY 12520 (US)
(74)
Representative:
Hirsch, Marc-Roger, et al
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)
(54)
PRODUCTION AND RECOVERY OF RECOMBINANT NEUROTROPHINS