(19)
(11) EP 0 590 059 A1

(12)

(43) Date of publication:
06.04.1994 Bulletin 1994/14

(21) Application number: 92914222.0

(22) Date of filing: 11.06.1992
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
C07K 14/ 475( . )
C07K 14/ 52( . )
C12P 21/ 02( . )
C07K 14/ 245( . )
C07K 14/ 48( . )
C12N 15/ 70( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1992/005006
(87) International publication number:
WO 1992/022665 (23.12.1992 Gazette 1992/32)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 12.06.1991 US 19910715185
21.11.1991 US 19910796106

(71) Applicant: REGENERON PHARMACEUTICALS, INC.
Tarrytown, NY 10591-6707 (US)

(72) Inventors:
  • PANAYOTATOS, Nikos
    Orangeburg, NY 10962 (US)
  • FANDL, James, P.
    La Grangeville, NY 12520 (US)

(74) Representative: Hirsch, Marc-Roger, et al 
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)

   


(54) PRODUCTION AND RECOVERY OF RECOMBINANT NEUROTROPHINS