(19)
(11) EP 0 593 439 A1

(12)

(43) Date of publication:
27.04.1994 Bulletin 1994/17

(21) Application number: 90915243.0

(22) Date of filing: 14.08.1990
(51) International Patent Classification (IPC): 
C07D 493/ 04( . )
C07D 497/ 04( . )
(86) International application number:
PCT/US1990/004451
(87) International publication number:
WO 1991/004256 (04.04.1991 Gazette 1991/08)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 13.09.1989 US 19890406912

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventor:
  • HERRINGTON, Paul, M.
    Kalamazoo, MI 49002 (US)

(74) Representative: Perry, Robert Edward 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) GAMMA ALKYLATION OF A PROTECTED DERIVATIVE OF THE ENONE OF SPECTINOMYCIN