(19)
(11)
EP 0 593 439 A1
(12)
(43)
Date of publication:
27.04.1994
Bulletin 1994/17
(21)
Application number:
90915243.0
(22)
Date of filing:
14.08.1990
(51)
International Patent Classification (IPC):
C07D
493/
04
( . )
C07D
497/
04
( . )
(86)
International application number:
PCT/US1990/004451
(87)
International publication number:
WO 1991/004256
(
04.04.1991
Gazette 1991/08)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE
(30)
Priority:
13.09.1989
US 19890406912
(71)
Applicant:
THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)
(72)
Inventor:
HERRINGTON, Paul, M.
Kalamazoo, MI 49002 (US)
(74)
Representative:
Perry, Robert Edward
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)
(54)
GAMMA ALKYLATION OF A PROTECTED DERIVATIVE OF THE ENONE OF SPECTINOMYCIN