(19)
(11)
EP 0 594 677 A1
(12)
(43)
Date of publication:
04.05.1994
Bulletin 1994/18
(21)
Application number:
92914562.0
(22)
Date of filing:
03.06.1992
(51)
International Patent Classification (IPC):
C07D
473/
34
( . )
A61K
31/
70
( . )
A61K
31/
7052
( . )
A61K
31/
7068
( . )
A61K
31/
7076
( . )
A61K
31/
715
( . )
A61P
1/
16
( . )
C07D
405/
04
( . )
C07H
19/
067
( . )
C07H
19/
09
( . )
C07H
19/
167
( . )
C07H
19/
20
( . )
A61K
9/
127
( . )
A61K
31/
7042
( . )
A61K
31/
7064
( . )
A61K
31/
7072
( . )
A61K
31/
708
( . )
A61K
38/
00
( . )
A61P
31/
12
( . )
C07H
19/
04
( . )
C07H
19/
073
( . )
C07H
19/
10
( . )
C07H
19/
19
( . )
C07H
19/
207
( . )
(86)
International application number:
PCT/US1992/004856
(87)
International publication number:
WO 1993/000910
(
21.01.1993
Gazette 1993/03)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
(30)
Priority:
12.07.1991
US 19910730273
(71)
Applicant:
VICAL, INC.
San Diego California 92121 (US)
(72)
Inventor:
HOSTETLER, Karl Y.
Del Mar, CA 92014 (US)
(74)
Representative:
VOSSIUS & PARTNER
Siebertstrasse 4
D-81675 München
D-81675 München (DE)
(54)
ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B