(19)
(11) EP 0 595 798 A1

(12)

(43) Date of publication:
11.05.1994 Bulletin 1994/19

(21) Application number: 90917241.0

(22) Date of filing: 18.10.1990
(51) International Patent Classification (IPC): 
A61K 39/ 395( . )
A61P 35/ 00( . )
A61P 43/ 00( . )
C07K 14/ 00( . )
C07K 16/ 00( . )
C07K 16/ 30( . )
C07K 19/ 00( . )
C12N 5/ 08( . )
C12P 21/ 08( . )
 A61K 35/ 14( . )
A61P 35/ 02( . )
C07K 1/ 113( . )
C07K 14/ 705( . )
C07K 16/ 28( . )
C07K 16/ 46( . )
C12N 5/ 06( . )
C12N 15/ 02( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1990/005981
(87) International publication number:
WO 1991/005871 (02.05.1991 Gazette 1991/10)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 20.10.1989 US 19890424540

(71) Applicant: MEDAREX, INC.
West Lebanon, NH 03784 (US)

(72) Inventors:
  • FANGER, Michael, W.
    Lebanon, NH 03766 (US)
  • GUYRE, Paul, M.
    Hanover, NH 03755 (US)
  • BALL, Edward, D.
    Norwich, VT 05055 (US)

(74) Representative: Holdcroft, James Gerald, Dr. 
Graham Watt & Co. 3 Gray's Inn Square
London WC1R 5AH
London WC1R 5AH (GB)

   


(54) BISPECIFIC HETEROANTIBODIES WITH DUAL EFFECTOR FUNCTIONS