(19)
(11) EP 0 595 980 A1

(12)

(43) Date of publication:
11.05.1994 Bulletin 1994/19

(21) Application number: 92916391.0

(22) Date of filing: 23.07.1992
(51) International Patent Classification (IPC): 
A61K 31/ 55( . )
A61P 25/ 08( . )
C07D 403/ 04( . )
C07D 417/ 04( . )
A61P 21/ 02( . )
A61P 25/ 20( . )
C07D 403/ 14( . )
C07D 417/ 14( . )
(86) International application number:
PCT/GB1992/001366
(87) International publication number:
WO 1993/002078 (04.02.1993 Gazette 1993/04)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 25.07.1991 GB 19910161133

(71) Applicant: MERCK SHARP & DOHME LTD.
Hoddesdon Hertfordshire EN11 9BU (GB)

(72) Inventors:
  • FLETCHER, Stephen Robert, 10 Clipped Hedge
    Hertfordshire CM22 7EG (GB)
  • SHOWELL, Graham Andrew
    Hertfordshire AL7 4BB (GB)

(74) Representative: Cole, William Gwyn, et al 
European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road
Harlow Essex CM20 2QR
Harlow Essex CM20 2QR (GB)

   


(54) BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY