(19)
(11) EP 0 596 034 A1

(12)

(43) Date of publication:
11.05.1994 Bulletin 1994/19

(21) Application number: 92917747.0

(22) Date of filing: 21.07.1992
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
C07K 14/ 475( . )
C07K 14/ 52( . )
C12N 15/ 09( . )
C12P 21/ 02( . )
C12R 1/ 91( . )
A61P 25/ 02( . )
C07K 14/ 48( . )
C12N 15/ 00( . )
C12N 15/ 12( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1992/006136
(87) International publication number:
WO 1993/002206 (04.02.1993 Gazette 1993/04)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30) Priority: 23.07.1991 US 19910735538
30.08.1991 US 19910753176

(71) Applicant: SYNTEX-SYNERGEN NEUROSCIENCE JOINT VENTURE
Boulder, CO 80301 (US)

(72) Inventors:
  • COLLINS, Franklin, D.
    Boulder, CO 80304 (US)
  • RUSSELL, Deborah
    Boulder, CO 80303 (US)
  • MCDONALD, John, R.
    Boulder, CO 80302 (US)
  • FREUND, Erwin
    Berthoud, CO 80513 (US)
  • WILHELM, Larry, J.
    Boulder, CO 80303 (US)
  • BONAM, Duane, Mach
    Broomfield, CO 80020 (US)

(74) Representative: Lucas, Brian Ronald 
Lucas & Co. 135 Westhall Road
Warlingham Surrey CR6 9HJ
Warlingham Surrey CR6 9HJ (GB)

   


(54) PURIFICATION OF RECOMBINANT CILIARY NEUROTROPHIC FACTOR AND C-TERMINAL TRUNCATED CILIARY NEUROTROPHIC FACTOR AND METHODS FOR TREATING PERIPHERAL NERVE DAMAGE