(19)
(11) EP 0 597 845 A1

(12)

(43) Date of publication:
25.05.1994 Bulletin 1994/21

(21) Application number: 91910516.0

(22) Date of filing: 22.05.1991
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
C07K 1/ 20( . )
C07K 14/ 00( . )
C07K 14/ 495( . )
C07K 14/ 71( . )
C07K 14/ 82( . )
C12N 5/ 06( . )
C12P 21/ 00( . )
G01N 33/ 574( . )
A61P 35/ 00( . )
C07K 1/ 22( . )
C07K 14/ 435( . )
C07K 14/ 705( . )
C07K 14/ 715( . )
C07K 19/ 00( . )
C12N 15/ 09( . )
G01N 33/ 53( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1991/003443
(87) International publication number:
WO 1991/018921 (12.12.1991 Gazette 1991/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 25.05.1990 US 19900528438

(71) Applicant: GEORGETOWN UNIVERSITY
Washington, DC 20057 (US)

(72) Inventors:
  • LIPPMAN, Marc
    Bethesda, MD 20817 (US)
  • LUPU, Ruth
    Gaithersburg MD 20878 (US)

(74) Representative: Dost, Wolfgang, Dr.rer.nat., Dipl.-Chem., et al 
Patent- und Rechtsanwälte Bardehle . Pagenberg . Dost . Altenburg . Frohwitter . Geissler & Partner Postfach 86 06 20
D-81633 München
D-81633 München (DE)

   


(54) GROWTH FACTOR WHICH INHIBITS THE GROWTH OF CELLS OVEREXPRESSING THE HUMAN ONCOGENE erbB-2