T CELL RECEPTOR-BASED THERAPY FOR RHEUMATOID ARTHRITIS - Patent 0602178

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EP 0 602 178 A1

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(43)	Date of publication:
	22.06.1994 Bulletin 1994/25

(21)	Application number: 92919946.0

(22)	Date of filing: 27.08.1992

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International Patent Classification (IPC):

G01N 33/ 53^{( . )}
A61K 39/ 395^{( . )}
C07K 14/ 705^{( . )}
C07K 16/ 00^{( . )}
C12N 15/ 02^{( . )}
G01N 33/ 564^{( . )}

A61K 39/ 00^{( . )}
A61P 29/ 00^{( . )}
C07K 14/ 725^{( . )}
C07K 16/ 28^{( . )}
C12P 21/ 08^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/US1992/007289

(87)	International publication number:
	WO 1993/004695 (18.03.1993 Gazette 1993/08)

(84)	Designated Contracting States:
	AT CH DE FR GB IT LI

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Priority:

28.08.1991 US 19910750913
06.01.1992 US 19920817912

(71)	Applicants:
	THE WISTAR INSTITUTE Philadelphia Pennsylvania 19104 (US) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA Philadelphia, Pennsylvania 19104-3147 (US)

(72)	Inventors:
	WILLIAMS, William, V. Havertown, PA 19083 (US) WEINER, David, B. Merion, PA 19066 (US)

(74)	Representative: Stebbing, Peter John Hunter, et al
	Ablett & Stebbing 45 Lancaster Mews Lancaster Gate London W2 3QQ London W2 3QQ (GB)

(54)	T CELL RECEPTOR-BASED THERAPY FOR RHEUMATOID ARTHRITIS