(19)

(11)

EP 0 603 348 A1

(12)

(43) Date of publication: 29.06.1994 Bulletin 1994/26 (21) Application number: 93909822.0 (22) Date of filing: 12.05.1993

(51) International Patent Classification (IPC):  A61K 31/ 70( . ) A61K 31/ 7052( . ) A61P 9/ 00( . ) A61P 25/ 00( . ) C07H 19/ 167( . ) A61K 31/ 7042( . ) A61K 31/ 7076( . ) A61P 9/ 10( . ) C07H 19/ 16( . ) (86) International application number: PCT/DK1993/000158 (87) International publication number: WO 1993/023418 (25.11.1993 Gazette 1993/28)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 14.05.1992 DK 19920000626 (71) Applicant: NOVO NORDISK A/S DK-2880 Bagsvaerd (DK)	(72) Inventors: KNUTSEN, Lars, Jacob, Stray DK-2950 Vedb k (DK) LAU, Jesper DK-2530 Farum (DK)