(19)

(11)

EP 0 603 377 A1

(12)

(43) Date of publication: 29.06.1994 Bulletin 1994/26 (21) Application number: 93915749.0 (22) Date of filing: 30.06.1993

(51) International Patent Classification (IPC):  A01N 43/ 78( . ) A61P 33/ 10( . ) C07D 513/ 04( . ) A61K 31/ 425( . ) C07D 417/ 12( . ) (86) International application number: PCT/EP1993/001682 (87) International publication number: WO 1994/001432 (20.01.1994 Gazette 1994/03)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 13.07.1992 CH 19920000022 (71) Applicant: CIBA-GEIGY AG CH-4002 Basel (CH)	(72) Inventors: HILDENBRAND, Christof CH-4054 Basle (CH) GEHRET, Jean-Claude CH-4147 Aesch (CH) TINEMBART, Olivier CH-2800 Delémont (CH)