METHODS OF IMPROVING ALLOGRAFT OR XENOGRAFT TOLERANCE BY ADMINISTRATION OF AN LFA-3 OR CD2 BINDING PROTEIN - Patent 0607353

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EP 0 607 353 A1

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(43)	Date of publication:
	27.07.1994 Bulletin 1994/30

(21)	Application number: 92922682.0

(22)	Date of filing: 06.10.1992

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International Patent Classification (IPC):

A61K 38/ 00^{( . )}
A61K 38/ 17^{( . )}
A61K 45/ 00^{( . )}
A61P 13/ 12^{( . )}
A61P 37/ 06^{( . )}
C07K 14/ 705^{( . )}

A61K 31/ 573^{( . )}
A61K 39/ 395^{( . )}
A61P 9/ 00^{( . )}
A61P 37/ 00^{( . )}
A61P 43/ 00^{( . )}
C07K 16/ 28^{( . )}

(86)	International application number:
	PCT/US1992/008754

(87)	International publication number:
	WO 1993/006852 (15.04.1993 Gazette 1993/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE

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Priority:

07.10.1991 US 19910772705
12.03.1992 US 19920850706

(60)	Divisional application:
	96117245.9 / 0786255

(71)	Applicant: BIOGEN, INC.
	Cambridge Massachusetts 02142 (US)

(72)	Inventors:
	WALLNER, Barbara, P. Cambridge, MA 02139 (US) BENJAMIN, Christopher, D. Beverly, MA 01915 (US)

(74)	Representative: Pett, Christopher Phineas
	Frank B. Dehn & Co. European Patent Attorneys Imperial House 15-19 Kingsway London WC2B 6UZ London WC2B 6UZ (GB)

(54)	METHODS OF IMPROVING ALLOGRAFT OR XENOGRAFT TOLERANCE BY ADMINISTRATION OF AN LFA-3 OR CD2 BINDING PROTEIN