(19)
(11)
EP 0 607 408 A1
(12)
(43)
Date of publication:
27.07.1994
Bulletin 1994/30
(21)
Application number:
93918190.0
(22)
Date of filing:
13.07.1993
(51)
International Patent Classification (IPC):
G01N
33/
53
( . )
A61K
39/
00
( . )
A61K
39/
44
( . )
A61P
31/
12
( . )
C07K
1/
107
( . )
C07K
14/
195
( . )
C07K
16/
00
( . )
C07K
16/
10
( . )
C07K
16/
32
( . )
A61K
35/
12
( . )
A61K
39/
395
( . )
A61K
49/
00
( . )
A61P
37/
00
( . )
C07K
1/
113
( . )
C07K
14/
41
( . )
C07K
16/
08
( . )
C07K
16/
18
( . )
A61K
38/
00
( . )
(86)
International application number:
PCT/US1993/006599
(87)
International publication number:
WO 1994/001131
(
20.01.1994
Gazette 1994/03)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
13.07.1992
US 19920912453
(71)
Applicant:
EUKARION, INC.
Bedford, Massachusetts 01730 (US)
(72)
Inventor:
MALFROY-CAMINE, Bernard
Arlington, MA 02174 (US)
(74)
Representative:
Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Maximilianstrasse 58
D-80538 München
D-80538 München (DE)
(54)
TRANSVASCULAR AND INTRACELLULAR DELIVERY OF LIPIDIZED PROTEINS