(19)
(11) EP 0 609 211 A1

(12)

(43) Date of publication:
10.08.1994 Bulletin 1994/32

(21) Application number: 92904892.0

(22) Date of filing: 26.11.1991
(51) International Patent Classification (IPC): 
A61K 31/ 12( . )
A61K 31/ 166( . )
A61K 31/ 352( . )
A61P 31/ 12( . )
C07C 233/ 65( . )
C07D 311/ 12( . )
C07D 311/ 16( . )
A61K 31/ 165( . )
A61K 31/ 35( . )
A61K 31/ 44( . )
A61P 35/ 00( . )
C07D 217/ 24( . )
C07D 311/ 14( . )
C07D 311/ 18( . )
(86) International application number:
PCT/US1991/008902
(87) International publication number:
WO 1993/007868 (29.04.1993 Gazette 1993/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 22.10.1991 US 19910780809

(71) Applicants:
  • OCTAMER, INC.
    San Francisco, CA 94111 (US)
  • KUN, Ernest
    Mill Valley, CA 94941 (US)

(72) Inventors:
  • KUN, Ernest
    Mill Valley, CA 94941 (US)
  • MENDELEYEV, Jerome
    San Francisco, CA 94117 (US)
  • RICE, William, G.
    Sneelville, CA 30278 (US)

(74) Representative: Bizley, Richard Edward 
Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Bakers Lane
Epping Essex CM16 5DQ
Epping Essex CM16 5DQ (GB)

   


(54) ADENOSINE DIPHOSPHORIBOSE POLYMERASE BINDING NITROSO AROMATIC COMPOUNDS USEFUL AS ANTI-TUMOR AND ANTI-RETROVIRAL AGENTS