(19)

(11)

EP 0 613 377 A1

(12)

(43) Date of publication: 07.09.1994 Bulletin 1994/36 (21) Application number: 92922509.0 (22) Date of filing: 09.10.1992

(51) International Patent Classification (IPC):  A61K 47/ 30( . ) A61K 38/ 48( . ) A61L 15/ 32( . ) A61L 26/ 00( . ) A61K 38/ 43( . ) A61K 38/ 55( . ) A61L 24/ 10( . ) A61P 7/ 04( . ) (86) International application number: PCT/DK1992/000296 (87) International publication number: WO 1993/006855 (15.04.1993 Gazette 1993/10)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL SE (30) Priority: 11.10.1991 US 19910775664 (71) Applicant: NOVO NORDISK A/S DK-2880 Bagsvaerd (DK)	(72) Inventors: HEDDER, Ulla Karin Elisabeth S-216 20 Malmö (SE) OSTERGAARD, Erik Hagsbro DK-3500 Vaerlose (DK) EDWARDS, Martin William Woodenville, WA (US) (74) Representative: Thalsoe-Madsen, Kine Birgit, et al  c/o Novo Nordisk A/S Novo Allé DK-2880 Bagsvaerd DK-2880 Bagsvaerd (DK)