(19)

(11)

EP 0 616 530 A1

(12)

(43) Date of publication: 28.09.1994 Bulletin 1994/39 (21) Application number: 92923649.0 (22) Date of filing: 08.12.1992

(51) International Patent Classification (IPC):  A61K 31/ 40( . ) A61K 47/ 48( . ) (86) International application number: PCT/CA1992/000526 (87) International publication number: WO 1993/011763 (24.06.1993 Gazette 1993/15)

(84) Designated Contracting States: BE CH DE DK ES FR GB IE IT LI NL SE (30) Priority: 09.12.1991 CA 19912057289 02.09.1992 US 19920939317 (71) Applicant: Usher, Thomas Clemens Nassau (BS)	(72) Inventors: USHER, Thomas C. Nassau (BS) RESNICK, Lionel North Miami Beach, FL 33180 (US) BUSSO, Mariano Miami Beach, FL 33139 (US) (74) Representative: Allard, Susan Joyce, et al  BOULT, WADE & TENNANT 27 Furnival Street London EC4A 1PQ London EC4A 1PQ (GB)