(19)

(11)

EP 0 619 822 A1

(12)

(43) Date of publication: 19.10.1994 Bulletin 1994/42 (21) Application number: 92921860.0 (22) Date of filing: 15.10.1992

(51) International Patent Classification (IPC):  B01J 27/ 138( . ) C07B 61/ 00( . ) C07J 75/ 00( . ) B01J 27/ 26( . ) C07J 71/ 00( . ) (86) International application number: PCT/US1992/008638 (87) International publication number: WO 1993/011150 (10.06.1993 Gazette 1993/14)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 25.11.1991 US 19910797574 (71) Applicant: PFIZER INC. New York, N.Y. 10017 (US)	(72) Inventors: ALLEN, Douglas, John, M. New London, CT 06320 (US) BUSCH, Frank, Robert Gales Ferry, CT 06335 (US) LAMBERT, John, Francis North Stonington, CT 06359 (US) SHINE, Russell, James Waterford, CT 06385 (US) WALINSKY, Stanley, Walter Mystic, CT 06355 (US) (74) Representative: Bradbrook, Geoffrey William  PFIZER LIMITED Ramsgate Road Sandwich Kent, CT13 9NJ Sandwich Kent, CT13 9NJ (GB)