(19)

(11)

EP 0 619 823 A1

(12)

(43) Date of publication: 19.10.1994 Bulletin 1994/42 (21) Application number: 93900320.0 (22) Date of filing: 21.12.1992

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) C07K 1/ 06( . ) C07K 14/ 595( . ) A61P 3/ 04( . ) C07K 7/ 06( . ) (86) International application number: PCT/GB1992/002369 (87) International publication number: WO 1993/013126 (08.07.1993 Gazette 1993/16)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 20.12.1991 US 19910810985 29.09.1992 GB 19920020543 02.10.1992 GB 19920020761 (71) Applicant: FISONS CORPORATION Rochester, New York 14603 (US)	(72) Inventors: Pierson, Myles Edward Pittsford, New York 14534 (US) Rosamond, James Donald Honeoye, New York 14471 (US) (74) Representative: Hayles, James Richard  Fisons plc, 12 Derby Road Loughborough, Leicestershire LE11 0BB Loughborough, Leicestershire LE11 0BB (GB)