(19)

(11)

EP 0 620 819 A1

(12)

(43) Date of publication: 26.10.1994 Bulletin 1994/43 (21) Application number: 92923776.0 (22) Date of filing: 24.11.1992

(51) International Patent Classification (IPC):  A01N 43/ 90( . ) A61P 33/ 00( . ) C07D 493/ 22( . ) A61K 31/ 365( . ) A61P 33/ 10( . ) C07H 19/ 01( . ) (86) International application number: PCT/EP1992/002697 (87) International publication number: WO 1993/011129 (10.06.1993 Gazette 1993/14)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE (30) Priority: 04.12.1991 GB 19910025818 (71) Applicants: Pfizer Limited Sandwich Kent CT13 9NJ (GB) PFIZER HOSPITAL PRODUCTS, INC. New York, NY 10017 (US)	(72) Inventors: GIBSON, Stephen, Paul Sandwich Kent CT13 9NJ (GB) PERRY, David, Austen Sandwich Kent CT13 9NJ (GB) (74) Representative: Bradbrook, Geoffrey William  PFIZER LIMITED Ramsgate Road Sandwich Kent, CT13 9NJ Sandwich Kent, CT13 9NJ (GB)