(19)
(11)
EP 0 623 173 A1
(12)
(43)
Date of publication:
09.11.1994
Bulletin 1994/45
(21)
Application number:
93902915.0
(22)
Date of filing:
12.01.1993
(51)
International Patent Classification (IPC):
G01N
33/
577
( . )
A61P
29/
00
( . )
C07K
14/
52
( . )
C07K
16/
00
( . )
C07K
16/
28
( . )
C12N
5/
20
( . )
C12N
15/
09
( . )
C12P
21/
08
( . )
C12R
1/
91
( . )
A61K
39/
395
( . )
C07K
1/
22
( . )
C07K
14/
78
( . )
C07K
16/
24
( . )
C12N
5/
10
( . )
C12N
15/
02
( . )
C12P
21/
02
( . )
A61K
38/
00
( . )
(86)
International application number:
PCT/US1993/000031
(87)
International publication number:
WO 1993/014220
(
22.07.1993
Gazette 1993/18)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
13.01.1992
US 19920821712
(71)
Applicant:
BIOGEN, INC.
Cambridge Massachusetts 02142 (US)
(72)
Inventors:
OSBORN, Laurelee
Cambridge, MA 02141 (US)
BENJAMIN, Christopher, D.
Beverly, MA 01915 (US)
(74)
Representative:
Pett, Christopher Phineas
Frank B.Dehn & Co. Imperial House 15-19 Kingsway
London WC2B 6UZ
London WC2B 6UZ (GB)
(54)
ANTIBODIES RECOGNIZING THE FOURTH IMMUNOGLOBULIN-LIKE DOMAIN OF VCAM1