(19)

(11)

EP 0 625 154 A1

(12)

(43) Date of publication: 23.11.1994 Bulletin 1994/47 (21) Application number: 93902481.0 (22) Date of filing: 28.01.1993

(51) International Patent Classification (IPC):  C07D 473/ 40( . ) (86) International application number: PCT/GB1993/000185 (87) International publication number: WO 1993/015075 (05.08.1993 Gazette 1993/19)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 30.01.1992 GB 19920001961 (71) Applicant: SMITHKLINE BEECHAM PLC Brentford, Middlesex TW8 9EP (GB)	(72) Inventor: KILLEN, Christopher, Robert, James Worthing, West Sussex BN14 8QH (GB) (74) Representative: Tocher, Pauline  SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)