(19)

(11)

EP 0 628 011 A1

(12)

(43) Date of publication: 14.12.1994 Bulletin 1994/50 (21) Application number: 93906246.0 (22) Date of filing: 01.03.1993

(51) International Patent Classification (IPC):  A61J 1/ 03( . ) B65D 1/ 30( . ) (86) International application number: PCT/US1993/001741 (87) International publication number: WO 1993/017937 (16.09.1993 Gazette 1993/22)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE (30) Priority: 06.03.1992 US 19920846849 (71) Applicant: MERCK & CO. INC. Rahway New Jersey 07065-0900 (US)	(72) Inventor: BUNIN, Leonid Woodbridge, NJ 07095 (US) (74) Representative: Cole, William Gwyn, et al  European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road Harlow Essex CM20 2QR Harlow Essex CM20 2QR (GB)