SYNTHESIS OF IOVERSOL USING A MINIMAL EXCESS OF ACETOXYACETYLCHLORIDE - Patent 0628024

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EP 0 628 024 A1

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(43)	Date of publication:
	14.12.1994 Bulletin 1994/50

(21)	Application number: 93907271.0

(22)	Date of filing: 23.02.1993

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International Patent Classification (IPC):

A61K 49/ 04^{( . )}
C07C 237/ 46^{( . )}

C07C 231/ 02^{( . )}

(86)	International application number:
	PCT/US1993/002033

(87)	International publication number:
	WO 1993/016981 (02.09.1993 Gazette 1993/21)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE

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Priority:

28.02.1992 US 19920844042

(71)	Applicant: MALLINCKRODT MEDICAL, INC.
	St. Louis, MO 63134 (US)

(72)	Inventors:
	MC CARTHY, William, Z. St. Louis, MO 63104 (US) KNELLER, Mills, Thomas University City, MO 63130 (US) LIN, Youlin Chesterfield, MO 63017 (US) WALLACE, Rebecca, Abernathy Manchester, MO 63120 (US) WHITE, David, Hill Ballwin, MO 63011 (US)

(74)	Representative: Jones, Alan John
	CARPMAELS & RANSFORD 43 Bloomsbury Square London, WC1A 2RA London, WC1A 2RA (GB)

(54)	SYNTHESIS OF IOVERSOL USING A MINIMAL EXCESS OF ACETOXYACETYLCHLORIDE