(19)
(11) EP 0 629 190 A1

(12)

(43) Date of publication:
21.12.1994 Bulletin 1994/51

(21) Application number: 93902469.0

(22) Date of filing: 27.01.1993
(51) International Patent Classification (IPC): 
C07D 279/ 12( . )
A61K 31/ 445( . )
A61K 31/ 535( . )
A61P 3/ 00( . )
A61P 9/ 08( . )
A61P 25/ 04( . )
A61P 25/ 28( . )
C07D 211/ 18( . )
C07D 265/ 30( . )
C07D 451/ 02( . )
A61K 31/ 443( . )
A61K 31/ 451( . )
A61K 31/ 5375( . )
A61P 3/ 14( . )
A61P 9/ 10( . )
A61P 25/ 08( . )
C07D 211/ 14( . )
C07D 211/ 22( . )
C07D 405/ 12( . )
(86) International application number:
PCT/GB1993/000173
(87) International publication number:
WO 1993/015052 (05.08.1993 Gazette 1993/19)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 28.01.1992 GB 19920001744
28.01.1992 GB 19920001745
28.01.1992 GB 19920001746
28.01.1992 GB 19920001752

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • BROWN, Thomas, Henry SmithKline Beecham
    The Pinnacles Harlow Essex CM19 5AD (GB)
  • COOPER, David, Gwyn SmithKline Beecham
    Harlow Essex CM19 5AD (GB)
  • KING, Ronald, Joseph SmithKline Beecham
    Harlow Essex CM19 5AD (GB)
  • ORLEK, Barry, Sidney SmithKline Beecham
    Harlow Essex CM19 5AD (GB)

(74) Representative: Waters, David Martin, Dr., et al 
Smithkline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS