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(11)

EP 0 630 261 A1

(12)

(43) Date of publication: 28.12.1994 Bulletin 1994/52 (21) Application number: 93905115.0 (22) Date of filing: 09.03.1993

(51) International Patent Classification (IPC):  A61K 31/ 05( . ) A61K 47/ 48( . ) A61K 31/ 57( . ) (86) International application number: PCT/AU1993/000100 (87) International publication number: WO 1993/017711 (16.09.1993 Gazette 1993/22)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 11.03.1992 AU 19920001288 15.04.1992 AU 19920001915 29.04.1992 AU 19920002182 20.07.1992 AU 19920003612 23.07.1992 AU 19920003674 23.07.1992 AU 19920003673 31.07.1992 AU 19920003836 17.08.1992 AU 19920004119 31.08.1992 AU 19920004409 17.09.1992 AU 19920004747 02.02.1993 AU 19930007061 (71) Applicant: AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED Brisbane, QLD 4001 (AU)

(72) Inventors: PALMER, Clive, Frederick Broadbeach Waters, QLD 4218 (AU) HO, Paul, Chi, Cui Carseldine, QLD 5085 (AU) BROWN, Susan, Elisabeth, Enfield, S.A. 5085 (AU) MAY, Bruce, Lindley Greenborough, VIC 3052 (AU) SCHIESSER, Deborah, Susanne Reno, NV 89503 (US) LUO, Yin Pullman WA 99163 (US) DENNIS, Nicholas Mudgeeraba, QLD 4312 (AU) LINCOLN, Stephen, Frederick Stony Fell, S.A. 5066 (AU) COATES, John, Hewlett North Adelaide, S.A. 5006 (AU) EASTON, Christopher, John Bellevue Heights, S.A. 5050 (AU) DUCKWORTH, Paul Toowong, QLD 4066 (AU) WANG, Peng Kent Town SA 5067 (AU) COGHLAN, Daniel, R., Seacombe Heights SA 5047 (AU) JANOWSKI, Wit Clovelly Park, S.A. 5042 (AU) LEPORE, Angelo Magill, S.A. 5072 (AU) WILLIAMS, Michael, Lloyd Brompton, S.A. 5007 (AU) VAN EYK, Steven, John, D-6704 Mutterstadt (DE) (74) Representative: Grünecker, August, Dipl.-Ing.  Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner Maximilianstrasse 58 D-80538 München D-80538 München (DE)