(19)
(11) EP 0 638 081 A1

(12)

(43) Date of publication:
15.02.1995 Bulletin 1995/07

(21) Application number: 93908747.0

(22) Date of filing: 05.04.1993
(51) International Patent Classification (IPC): 
C07D 489/ 02( . )
A61P 25/ 30( . )
A61K 31/ 485( . )
C07D 489/ 08( . )
(86) International application number:
PCT/US1993/003221
(87) International publication number:
WO 1993/021188 (28.10.1993 Gazette 1993/26)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 13.04.1992 US 19920867997

(71) Applicant: THE REGENTS OF THE UNIVERSITY OF MINNESOTA
Minneapolis, Minnesota 55455 (US)

(72) Inventor:
  • PORTOGHESE, Philip, S.
    St. Paul, MN 55127 (US)

(74) Representative: Austin, Hedley William 
Urquhart-Dykes & Lord Alexandra House 1 Alexandra Road
Swansea West Glamorgan SA1 5ED
Swansea West Glamorgan SA1 5ED (GB)

   


(54) DELTA OPIOID RECEPTOR-SELECTIVE BENZYLIDENE-SUBSTITUTED MORPHINANS FOR THE TREATMENT OF ALCOHOL ABUSE