(19)
(11) EP 0 638 084 A1

(12)

(43) Date of publication:
15.02.1995 Bulletin 1995/07

(21) Application number: 94909033.0

(22) Date of filing: 21.02.1994
(51) International Patent Classification (IPC): 
A61K 31/ 66( . )
C07F 9/ 40( . )
C07F 9/ 6571( . )
 A61P 9/ 10( . )
C07F 9/ 44( . )
C07F 9/ 6574( . )
(86) International application number:
PCT/EP1994/000520
(87) International publication number:
WO 1994/019358 (01.09.1994 Gazette 1994/20)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 19.02.1993 CH 19930000521

(71) Applicant: SYMPHAR S.A.
CH-1290 VERSOIX (CH)

(72) Inventors:
  • NGUYEN, Lân
    CH-1260 Nyon (CH)
  • DIEP, Vinh, Van
    F-74100 Vétraz-Monthoux (FR)
  • PHAN, Hieu
    CH-1295 Tannay (CH)
  • FLORET, Simon
    F-01210 Versonnex (FR)
  • AZOULAY, Raymond
    CH-1260 Nyon (CH)
  • GUYON-GELLIN, Yves
    F-74100 Annemasse (FR)
  • MAECHLER, Pierre
    CH-1228 Plan-les-Ouates (CH)
  • NIESOR, Eric
    CH-1260 Nyon (CH)
  • BENTZEN, Craig, L.
    CH-1261 Bogis-Bossey (CH)

(74) Representative: Connell, Anthony Christopher, et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM