(19)
(11) EP 0 641 319 A1

(12)

(43) Date of publication:
08.03.1995 Bulletin 1995/10

(21) Application number: 93906530.0

(22) Date of filing: 13.03.1993
(51) International Patent Classification (IPC): 
A61K 31/ 395( . )
A61K 31/ 445( . )
A61P 31/ 12( . )
C07D 205/ 04( . )
C07D 207/ 404( . )
C07D 211/ 58( . )
C07D 307/ 33( . )
C07D 405/ 10( . )
C07D 407/ 10( . )
C07F 7/ 18( . )
A61K 31/ 397( . )
A61K 31/ 4468( . )
A61P 37/ 04( . )
C07D 205/ 08( . )
C07D 211/ 26( . )
C07D 211/ 74( . )
C07D 401/ 12( . )
C07D 405/ 12( . )
C07D 409/ 12( . )
C07D 207/ 40( . )
(86) International application number:
PCT/EP1993/000592
(87) International publication number:
WO 1993/023373 (25.11.1993 Gazette 1993/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 20.05.1992 GB 19920010744

(71) Applicants:
  • Pfizer Limited
    Sandwich Kent CT13 9NJ (GB)
  • PFIZER INC.
    New York, N.Y. 10017 (US)

(72) Inventors:
  • GREENGRASS, Colin, William
    Sandwich Kent CT13 9NJ (GB)
  • GYMER, Geoffrey, William Pfizer Central Research
    Sandwich Kent CT13 9NJ (GB)
  • HOOPLE, David, William, Thomas
    Sandwich Kent CT13 9NJ (GB)
  • STREET, Stephen, Derek, Albert
    Sandwich Kent CT13 9NJ (GB)
  • WHITTLE, Peter, John Pfizer Central Research
    Sandwich Kent CT13 9NJ (GB)

(74) Representative: Moore, James William, Dr., et al 
Pfizer Limited Ramsgate Road
Sandwich Kent CT13 9NJ
Sandwich Kent CT13 9NJ (GB)

   


(54) N- N'-(5-AMINO-4-HYDROXY-ACYLOYL)-$g(a)-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS