(19)
(11) EP 0 641 344 A1

(12)

(43) Date of publication:
08.03.1995 Bulletin 1995/10

(21) Application number: 93910221.0

(22) Date of filing: 18.05.1993
(51) International Patent Classification (IPC): 
A61K 31/ 52( . )
A61P 29/ 00( . )
A61P 37/ 04( . )
A61K 31/ 522( . )
A61P 31/ 12( . )
C07D 473/ 06( . )
(86) International application number:
PCT/GB1993/001014
(87) International publication number:
WO 1993/023401 (25.11.1993 Gazette 1993/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 21.05.1992 GB 19920010839

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventor:
  • FENWICK, Ashley, Edward SmithKline Beecham Pharm.
    Surrey KT18 5XQ (GB)

(74) Representative: Rutter, Keith, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) 8-SUBSTITUTED ANTHINES AS PHOSPHODIESTERASE INHIBITORS