(19)
(11)
EP 0 641 354 A1
(12)
(43)
Date of publication:
08.03.1995
Bulletin 1995/10
(21)
Application number:
92925362.0
(22)
Date of filing:
20.11.1992
(51)
International Patent Classification (IPC):
C07H
21/
02
( . )
C07H
21/
04
( . )
C07H
21/
00
( . )
C12Q
1/
68
( . )
(86)
International application number:
PCT/US1992/010043
(87)
International publication number:
WO 1993/011148
(
10.06.1993
Gazette 1993/14)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE
(30)
Priority:
25.11.1991
US 19910796804
(71)
Applicant:
PHARMAGENICS, INC.
Allendale, New Jersey 07401 (US)
(72)
Inventors:
COOK, Alan, F.
Cedar Grove, NJ 07009 (US)
FATHI, Reza
Newark, NJ 07104 (US)
(74)
Representative:
Segeth, Wolfgang
Patentanwälte Louis, Pöhlau, Lohrentz & Segeth Postfach 30 55
D-90014 Nürnberg
D-90014 Nürnberg (DE)
(54)
OLIGONUCLEOTIDES HAVING AMINOHYDROCARBON PHOSPHONATE MOIETIES