METHODS FOR DETECTING AND ISOLATING uPA-R AND INHIBITING THE BINDING OF uPA TO uPA-R - Patent 0642354

(19)

(11)

EP 0 642 354 A1

(12)

(43)	Date of publication:
	15.03.1995 Bulletin 1995/11

(21)	Application number: 92922134.0

(22)	Date of filing: 27.10.1992

(51)

International Patent Classification (IPC):

A61K 39/ 395^{( . )}
C07K 14/ 705^{( . )}
C12N 9/ 72^{( . )}
G01N 33/ 53^{( . )}
A61K 38/ 00^{( . )}

A61P 29/ 00^{( . )}
C07K 16/ 28^{( . )}
C12P 21/ 08^{( . )}
G01N 33/ 573^{( . )}

(86)	International application number:
	PCT/US1992/008977

(87)	International publication number:
	WO 1993/009808 (27.05.1993 Gazette 1993/13)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE

(30)

Priority:

18.11.1991 US 19910793208

(71)	Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
	Ann Arbor, Michigan 48109-1248 (US)

(72)	Inventors:
	MIZUKAMI, Ikuko, F. Ann Arbor, MI 48104 (US) TODD, Robert, F., III Ann Arbor, MI 48103 (US)

(74)	Representative: Des Termes, Monique, et al
	c/o Société de Protection des Inventions 25, rue de Ponthieu F-75008 Paris F-75008 Paris (FR)

(54)	METHODS FOR DETECTING AND ISOLATING uPA-R AND INHIBITING THE BINDING OF uPA TO uPA-R