(19)
(11) EP 0 643 586 A1

(12)

(43) Date of publication:
22.03.1995 Bulletin 1995/12

(21) Application number: 93914155.0

(22) Date of filing: 26.05.1993
(51) International Patent Classification (IPC): 
G01N 33/ 569( . )
A61K 39/ 02( . )
A61P 31/ 00( . )
C07K 14/ 20( . )
C12N 15/ 02( . )
C12P 21/ 08( . )
C12R 1/ 01( . )
 A61K 39/ 00( . )
A61K 39/ 395( . )
C07K 14/ 195( . )
C07K 16/ 12( . )
C12P 21/ 00( . )
A61K 38/ 00( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1993/004984
(87) International publication number:
WO 1993/024145 (09.12.1993 Gazette 1993/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 26.05.1992 US 19920889015
14.09.1992 US 19920944464
18.12.1992 US 19920992896

(71) Applicants:
  • SMITHKLINE BEECHAM CORPORATION
    King of Prussia, PA 19406-0939 (US)
  • THE GOVERNMENT OF THE USA represented by THE DEPARTMENT OF HEALTH AND HUM AN SERVICES CENTERS FOR DISEASE CONTROL & PREVENTION
    Atlanta, GA 30333 (US)

(72) Inventors:
  • GOLDE, William, T.
    Boulder, CO 80304 (US)
  • ROEHRIG, John, T.
    Fort Collins, CO 80526 (US)
  • BURKOT, Thomnas
    Fort Collins, CO 80526 (US)
  • PIESMAN, Joseph, F.
    Fort Collins, CO 80524 (US)
  • JOHNSON, Barbara, J., B.
    Fort Collins, CO 80525 (US)
  • MAYER, Leonard, W.
    Fort Collins, CO 80525 (US)
  • KEEN, Mark, G.
    Flemington, NJ 08822 (US)
  • HUNT, Ann, R.
    Fort Collins, CO 80526 (US)

(74) Representative: Russell, Brian John 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) COMPOSITIONS USEFUL IN DIAGNOSIS AND PROPHYLAXIS OF LYME DISEASE