(19)
(11) EP 0 643 768 A1

(12)

(43) Date of publication:
22.03.1995 Bulletin 1995/12

(21) Application number: 93912092.0

(22) Date of filing: 29.03.1993
(51) International Patent Classification (IPC): 
A01K 67/ 027( . )
C07K 14/ 705( . )
C12N 15/ 113( . )
C07H 21/ 04( . )
C12N 15/ 09( . )
C12N 15/ 85( . )
(86) International application number:
PCT/US1993/002913
(87) International publication number:
WO 1993/021309 (28.10.1993 Gazette 1993/26)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 10.04.1992 US 19920866677

(71) Applicant: DUZ PARTNERSHIP
San Francisco, CA 94166 (US)

(72) Inventors:
  • LEE, Nancy, M.
    San Francisco, CA 94116 (US)
  • LOH, Horace, H.
    San Francisco, CA 94116 (US)
  • LIPPMAN, David
    Stockton, CA 95204 (US)

(74) Representative: Greaves, Carol Pauline 
Mewburn Ellis York House 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) OLIGONUCLEOTIDE SEQUENCES AND TRANSGENIC ANIMALS TRANSFECTED THEREWITH HAVING REDUCED SENSITIVITY TO NARCOTIC ANALGESICS