(19)
(11) EP 0 644 765 A1

(12)

(43) Date of publication:
29.03.1995 Bulletin 1995/13

(21) Application number: 93914110.0

(22) Date of filing: 21.05.1993
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 48/ 00( . )
A61P 27/ 02( . )
A61P 43/ 00( . )
A61K 31/ 70( . )
A61P 1/ 00( . )
A61P 29/ 00( . )
C12N 15/ 113( . )
(86) International application number:
PCT/US1993/004917
(87) International publication number:
WO 1993/024134 (09.12.1993 Gazette 1993/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 22.05.1992 US 19920887734

(71) Applicants:
  • GENTA INCORPORATED
    San Diego, CA 92121 (US)
  • UNIVERSITY OF MICHIGAN
    Ann Arbor, MI 48109-1248 (US)

(72) Inventors:
  • COOPER, Kevin, D.
    Ann Arbor, MI 48105 (US)
  • HAMMERBERG, Craig
    Manchester, MI 48159 (US)
  • MAXWELL, Kameron, W.
    Rancho Santa Fe, CA 92067 (US)
  • TSENG, Ben, Y.
    San Diego, CA 92130 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) TREATMENT OF CELLULAR HYPERPROLIFERATION BY INHIBITION OF INTERLEUKIN-1