(19)
(11)
EP 0 644 892 A1
(12)
(43)
Date of publication:
29.03.1995
Bulletin 1995/13
(21)
Application number:
93909587.0
(22)
Date of filing:
23.04.1993
(51)
International Patent Classification (IPC):
A61K
31/
4427
( . )
A61K
38/
55
( . )
A61P
9/
08
( . )
A61P
9/
12
( . )
A61P
15/
00
( . )
C07K
5/
02
( . )
C07K
5/
065
( . )
C07K
5/
083
( . )
C07K
5/
097
( . )
A61K
38/
00
( . )
A61K
31/
445
( . )
A61P
9/
00
( . )
A61P
9/
10
( . )
A61P
13/
02
( . )
C07D
401/
06
( . )
C07K
5/
06
( . )
C07K
5/
078
( . )
C07K
5/
087
( . )
C07K
14/
81
( . )
(86)
International application number:
PCT/US1993/003625
(87)
International publication number:
WO 1993/025574
(
23.12.1993
Gazette 1993/30)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
(30)
Priority:
12.06.1992
US 19920897723
(71)
Applicant:
PFIZER INC.
New York, N.Y. 10017 (US)
(72)
Inventor:
HOOVER, Dennis, J.
Stonington, CT 06378 (US)
(74)
Representative:
Moore, James William, Dr., et al
Pfizer Limited Ramsgate Road
Sandwich Kent CT13 9NJ
Sandwich Kent CT13 9NJ (GB)
(54)
INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE