(19)
(11) EP 0 644 892 A1

(12)

(43) Date of publication:
29.03.1995 Bulletin 1995/13

(21) Application number: 93909587.0

(22) Date of filing: 23.04.1993
(51) International Patent Classification (IPC): 
A61K 31/ 4427( . )
A61K 38/ 55( . )
A61P 9/ 08( . )
A61P 9/ 12( . )
A61P 15/ 00( . )
C07K 5/ 02( . )
C07K 5/ 065( . )
C07K 5/ 083( . )
C07K 5/ 097( . )
A61K 38/ 00( . )
A61K 31/ 445( . )
A61P 9/ 00( . )
A61P 9/ 10( . )
A61P 13/ 02( . )
C07D 401/ 06( . )
C07K 5/ 06( . )
C07K 5/ 078( . )
C07K 5/ 087( . )
C07K 14/ 81( . )
(86) International application number:
PCT/US1993/003625
(87) International publication number:
WO 1993/025574 (23.12.1993 Gazette 1993/30)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 12.06.1992 US 19920897723

(71) Applicant: PFIZER INC.
New York, N.Y. 10017 (US)

(72) Inventor:
  • HOOVER, Dennis, J.
    Stonington, CT 06378 (US)

(74) Representative: Moore, James William, Dr., et al 
Pfizer Limited Ramsgate Road
Sandwich Kent CT13 9NJ
Sandwich Kent CT13 9NJ (GB)

   


(54) INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE