(19)

(11)

EP 0 646 031 A1

(12)

(43) Date of publication: 05.04.1995 Bulletin 1995/14 (21) Application number: 93914410.0 (22) Date of filing: 08.06.1993

(51) International Patent Classification (IPC):  A61M 25/ 00( . ) A61M 16/ 04( . ) A61M 29/ 02( . ) (86) International application number: PCT/US1993/005396 (87) International publication number: WO 1993/025265 (23.12.1993 Gazette 1993/30)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE (30) Priority: 12.06.1992 US 19920897635 05.03.1993 US 19930026929 (71) Applicant: MALLINCKRODT MEDICAL, INC. St. Louis, MO 63134 (US)	(72) Inventors: BURLEIGH, B., Daniel O'Fallon, MO 63366 (US) LYLE, Leon, R. Webster Groves, MO 63119 (US) (74) Representative: Jones, Alan John, et al  CARPMAELS & RANSFORD 43 Bloomsbury Square London, WC1A 2RA London, WC1A 2RA (GB)