(19)
(11) EP 0 646 125 A1

(12)

(43) Date of publication:
05.04.1995 Bulletin 1995/14

(21) Application number: 93912478.0

(22) Date of filing: 18.06.1993
(51) International Patent Classification (IPC): 
C07D 473/ 04( . )
A61K 31/ 52( . )
A61K 31/ 70( . )
C07D 405/ 04( . )
C07H 19/ 04( . )
A61K 31/ 505( . )
A61K 31/ 522( . )
A61P 31/ 12( . )
C07D 473/ 00( . )
(86) International application number:
PCT/BE1993/000036
(87) International publication number:
WO 1993/025565 (23.12.1993 Gazette 1993/30)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 18.06.1992 EP 19920201803

(71) Applicant: Stichting REGA V.Z.W.
B-3000 Leuven (BE)

(72) Inventors:
  • DE CLERCQ, Erik, Désiré, Alice
    B-3360 Lovenjoel (BE)
  • HERDEWIJN, Piet, André, Maurits
    B-3111 Rotselaar (Wezemaal) (BE)
  • VAN AERSCHOT, Arthur, Albert, Edgard
    B-2220 Heist o/d Berg (BE)

(74) Representative: Van Someren, Petronella F. H. M., et al 
Arnold & Siedsma, Advocaten en Octrooigemachtigden, Sweelinckplein 1
NL-2517 GK Den Haag
NL-2517 GK Den Haag (NL)

   


(54) 1,5-ANHYDROHEXITOL NUCLEOSIDE ANALOGUES AND PHARMACEUTICAL USE THEREOF