(19)

(11)

EP 0 646 173 A1

(12)

(43) Date of publication: 05.04.1995 Bulletin 1995/14 (21) Application number: 93909677.0 (22) Date of filing: 19.05.1993

(51) International Patent Classification (IPC):  C07K 14/ 155( . ) C07K 14/ 47( . ) C07K 19/ 00( . ) C12N 15/ 09( . ) C12N 15/ 62( . ) G01N 33/ 531( . ) C12R 1/ 19( . ) C07K 14/ 16( . ) C07K 16/ 00( . ) C12N 1/ 21( . ) C12N 15/ 13( . ) C12P 21/ 00( . ) G01N 33/ 68( . ) (86) International application number: PCT/AU1993/000228 (87) International publication number: WO 1993/024630 (09.12.1993 Gazette 1993/29)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 22.05.1992 AU 1992PL02551 (71) Applicant: AGEN LIMITED Acacia Ridge Queensland 4110 (AU)	(72) Inventors: LILLEY, Glenn, George Upper Plenty, VIC 3756 (AU) HUDSON, Peter, John Donvale, VIC 3111 (AU) HILLYARD, Carmel, Judith Paddington, QLD 4064 (AU) (74) Representative: Hansen, Bernd, Dr. Dipl.-Chem.  Hoffmann, Eitle & Partner, Patentanwälte, Arabellastrasse 4 D-81925 München D-81925 München (DE)