(19)

(11)

EP 0 648 125 A1

(12)

(43) Date of publication: 19.04.1995 Bulletin 1995/16 (21) Application number: 93910198.0 (22) Date of filing: 14.05.1993

(51) International Patent Classification (IPC):  A61K 38/ 43( . ) A61P 29/ 00( . ) A61K 38/ 37( . ) (86) International application number: PCT/GB1993/000990 (87) International publication number: WO 1993/024137 (09.12.1993 Gazette 1993/29)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 01.06.1992 GB 19920011538 (71) Applicant: BRITISH TECHNOLOGY GROUP LIMITED London SE1 6BU (GB)	(72) Inventors: BLAKE, David Russell Droitwich, West Midlands WR9 7BE (GB) MORRIS, Christopher John West Midlands B73 5LA (GB) WILLIAMS, Richard, Bartholomew Hereford HR1 2TU (GB) WINYARD, Paul Graham Enfield, Middlesex EN1 1PD (GB) (74) Representative: Wallace, Sheila Jane  Patents Department British Technology Group Limited 101 Newington Causeway GB-London SE1 6BU GB-London SE1 6BU (GB)