(19)
(11) EP 0 650 368 A1

(12)

(43) Date of publication:
03.05.1995 Bulletin 1995/18

(21) Application number: 93915482.0

(22) Date of filing: 24.06.1993
(51) International Patent Classification (IPC): 
A61K 31/ 365( . )
A61K 45/ 00( . )
A61P 9/ 00( . )
A61P 27/ 02( . )
A61P 35/ 00( . )
 A61K 38/ 55( . )
A61K 48/ 00( . )
A61P 9/ 12( . )
A61P 27/ 12( . )
A61P 43/ 00( . )
(86) International application number:
PCT/US1993/006143
(87) International publication number:
WO 1994/000095 (06.01.1994 Gazette 1994/02)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 24.06.1992 US 19920903800
16.03.1993 US 19930034996
01.06.1993 US 19930072609

(71) Applicants:
  • CORTEX PHARMACEUTICALS, INC.
    Irvine, CA 92718 (US)
  • GEORGIA TECH RESEARCH CORPORATION
    Atlanta, GA 30332-0420 (US)

(72) Inventors:
  • EVELETH, David, D., Jr.
    Mission Viejo, CA 92692 (US)
  • LYNCH, Gary
    Irvine, CA 92715 (US)
  • POWERS, James, C.
    Atlanta, GA 30318 (US)
  • BARTUS, Raymond, T.
    Sudbury, MA 01776 (US)

(74) Representative: VOSSIUS & PARTNER 
Postfach 86 07 67
D-81634 München
D-81634 München (DE)

   


(54) USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH INCREASED CALPAIN ACTIVITY