(19)
(11)
EP 0 650 377 A1
(12)
(43)
Date of publication:
03.05.1995
Bulletin 1995/18
(21)
Application number:
93917095.0
(22)
Date of filing:
12.07.1993
(51)
International Patent Classification (IPC):
A61M
31/
00
( . )
A61K
9/
00
( . )
A61K
31/
195
( . )
A61M
37/
00
( . )
C12N
5/
00
( . )
C12N
5/
0793
( . )
A61F
2/
02
( . )
A61K
9/
22
( . )
A61K
35/
12
( . )
B01J
13/
02
( . )
C12N
5/
071
( . )
C12N
11/
04
( . )
(86)
International application number:
PCT/US1993/006512
(87)
International publication number:
WO 1994/001166
(
20.01.1994
Gazette 1994/03)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
13.07.1992
US 19920912463
(71)
Applicant:
BROWN UNIVERSITY RESEARCH FOUNDATION
Providence, RI 02912 (US)
(72)
Inventors:
AEBISCHER, Patrick
Barrington, RI 02806 (US)
TRESCO, Patrick A.
Salt Lake City, UT 84117 (US)
(74)
Representative:
Allard, Susan Joyce, et al
BOULT, WADE & TENNANT 27 Furnival Street
London EC4A 1PQ
London EC4A 1PQ (GB)
(54)
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