FORMATION OF TRIPLE HELIX COMPLEXES OF SINGLE STRANDED NUCLEIC ACIDS USING NUCLEOSIDE OLIGOMERS - Patent 0650526

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EP 0 650 526 A1

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(43)	Date of publication:
	03.05.1995 Bulletin 1995/18

(21)	Application number: 92921942.0

(22)	Date of filing: 05.10.1992

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
C12N 15/ 113^{( . )}
C12Q 1/ 70^{( . )}

C07H 21/ 00^{( . )}
C12Q 1/ 68^{( . )}

(86)	International application number:
	PCT/US1992/008458

(87)	International publication number:
	WO 1993/007295 (15.04.1993 Gazette 1993/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE

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Priority:

07.10.1991 US 19910772081

(71)	Applicants:
	THE JOHNS HOPKINS UNIVERSITY Baltimore, MD 21218-2692 (US) GENTA INCORPORATED San Diego, CA 92121 (US)

(72)	Inventors:
	TS'O, Paul, On-Pong Ellicott City, MD 21042 (US) ADAMS, Thomas, Henry Rancho Sante Fe, CA 92067 (US) ARNOLD, Lyle, J., Jr. Poway, CA 92064 (US)

(74)	Representative: Goldin, Douglas Michael, et al
	J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)

(54)	FORMATION OF TRIPLE HELIX COMPLEXES OF SINGLE STRANDED NUCLEIC ACIDS USING NUCLEOSIDE OLIGOMERS