(19)
(11) EP 0 651 750 A1

(12)

(43) Date of publication:
10.05.1995 Bulletin 1995/19

(21) Application number: 93916105.0

(22) Date of filing: 19.07.1993
(51) International Patent Classification (IPC): 
C07D 473/ 00( . )
A61K 31/ 403( . )
C07D 207/ 333( . )
C07D 209/ 94( . )
C07D 409/ 06( . )
C07D 491/ 04( . )
C07D 495/ 04( . )
A61K 31/ 40( . )
A61P 35/ 00( . )
C07D 207/ 34( . )
C07D 403/ 06( . )
C07D 487/ 04( . )
C07D 491/ 048( . )
C07D 207/ 32( . )
(86) International application number:
PCT/GB1993/001512
(87) International publication number:
WO 1994/002483 (03.02.1994 Gazette 1994/04)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 20.07.1992 GB 19920015361

(71) Applicants:
  • THE WELLCOME FOUNDATION LIMITED
    London NW1 2BP (GB)
  • UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED
    Cardiff CF1 1XR (GB)

(72) Inventors:
  • FRANZMANN, Karl Witold
    Beckenham, Kent BR3 3BS (GB)
  • STABLES, Jeremy Nigel
    Beckenham, Kent BR3 3BS (GB)
  • SHANNON, Patrick Vivian Richard
    Penarth, South Glamorgan CF64 1AT (GB)
  • RAO, Nagaraja Kodanda Ranganatha
    Birchgrove, Cardiff CF4 4QN (GB)
  • CHUNCHATPRASERT, Laddawan
    Khon Kaen 40000 (TH)

(74) Representative: Rollins, Anthony John 
Langley Court
Beckenham, Kent BR3 3BS
Beckenham, Kent BR3 3BS (GB)

   


(54) TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS