(19)
(11) EP 0 654 999 A1

(12)

(43) Date of publication:
31.05.1995 Bulletin 1995/22

(21) Application number: 93917786.0

(22) Date of filing: 11.08.1993
(51) International Patent Classification (IPC): 
C07D 271/ 12( . )
A61K 31/ 16( . )
A61K 31/ 40( . )
A61K 31/ 41( . )
A61K 31/ 4245( . )
A61P 31/ 04( . )
C07D 207/ 448( . )
C07D 315/ 00( . )
A61K 31/ 13( . )
A61K 31/ 365( . )
A61K 31/ 4015( . )
A61K 31/ 415( . )
A61K 45/ 00( . )
A61P 43/ 00( . )
C07D 313/ 00( . )
(86) International application number:
PCT/EP1993/002149
(87) International publication number:
WO 1994/004161 (03.03.1994 Gazette 1994/06)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 12.08.1992 IT 1992FI00167

(71) Applicant: BIOCINE S.p.A.
I-53100 Siena (IT)

(72) Inventors:
  • BUGNOLI, Massimo
    I-53100 Siena (IT)
  • MONTECUCCO, Cesare
    I-35121 Padova (IT)
  • PAPINI, Emanuele
    I-35121 Padova (IT)
  • RAPPUOLI, Rino
    I-53100 Siena (IT)

(74) Representative: Hallybone, Huw George, et al 
CARPMAELS AND RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) USE OF INHIBITORS OF VACUOLAR-TYPE H?+ ATPASES