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EP 0 658 162 A1

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(43) Date of publication: 21.06.1995 Bulletin 1995/25 (21) Application number: 93919700.0 (22) Date of filing: 02.09.1993

(51) International Patent Classification (IPC):  C07D 477/ 00( . ) A61K 31/ 40( . ) C07D 207/ 12( . ) C07D 477/ 20( . ) A61K 31/ 397( . ) A61P 31/ 04( . ) C07D 207/ 16( . ) (86) International application number: PCT/KR1993/000079 (87) International publication number: WO 1994/005667 (17.03.1994 Gazette 1994/07)

(84) Designated Contracting States: DE FR GB IT (30) Priority: 02.09.1992 KR 19150091092 (71) Applicant: DONG-A PHARM. CO., LTD. Dongdaemoon-ku Seoul 130-070 (KR)

(72) Inventors: CHANG, Min, Sun Songpa-ku, Seoul 138-229 (KR) LIM, Jon, In Suwon-si, Kyunggi-do 441-390 (KR) KIM, Nam, Sik Songtan-si, Kyunggi-do 459-110 (KR) SHIN, Hee, Chan Kwanak-ku, Seoul 151-014 (KR) KIM, Gye, Won Mapo-ku, Seoul 121-020 (KR) KIM, Ji, Young Kangseo-ku, Seoul 157-010 (KR) RHEE, Jae, Keol Suwon-si, Kyunggi-do 441-372 (KR) LEE, Chon, Woo Songpa-ku, Seoul 138-240 (KR) IM, Weon, Bin Suwon-si, Kyunggi-do 441-370 (KR) KIM, Dong, Sung Kyunggi-do 449-910 (KR) (74) Representative: Lyons, Andrew John, et al  ROYSTONS Tower Building Water Street Liverpool L3 1BA Liverpool L3 1BA (GB)