(19)
(11) EP 0 658 196 A1

(12)

(43) Date of publication:
21.06.1995 Bulletin 1995/25

(21) Application number: 94919295.0

(22) Date of filing: 27.05.1994
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
C07K 14/ 435( . )
C12N 15/ 86( . )
C07H 21/ 04( . )
C12N 7/ 00( . )
C12N 15/ 866( . )
(86) International application number:
PCT/US1994/006079
(87) International publication number:
WO 1994/028114 (08.12.1994 Gazette 1994/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 28.05.1993 US 19930070164

(71) Applicant: AMERICAN CYANAMID COMPANY
Wayne New Jersey 07470 (US)

(72) Inventors:
  • WEBB, Nancy, Roberson
    Skillman, NJ 08558 (US)
  • DIERKS, Peter, Michael
    Yardley, PA 19067 (US)

(74) Representative: Walters, Philip Bernard William 
Wyeth Laboratories, Patents & Trade Marks Department, Huntercombe Lane South, Taplow
Maidenhead, Berkshire SL6 0PH
Maidenhead, Berkshire SL6 0PH (GB)

   


(54) GENE INSERTION BY DIRECT LIGATION $i(IN VITRO)