(19)
(11)
EP 0 658 210 A1
(12)
(43)
Date of publication:
21.06.1995
Bulletin 1995/25
(21)
Application number:
93920291.0
(22)
Date of filing:
24.08.1993
(51)
International Patent Classification (IPC):
C12N
15/
09
( . )
C07K
14/
21
( . )
A61K
38/
00
( . )
A61K
47/
48
( . )
C12N
15/
87
( . )
(86)
International application number:
PCT/US1993/007945
(87)
International publication number:
WO 1994/004696
(
03.03.1994
Gazette 1994/06)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
25.08.1992
US 19920935074
(71)
Applicant:
MILES INC.
West Haven, CT 06516-4174 (US)
(72)
Inventors:
BARNETT, Thomas, R.
Prospect, CT 06712 (US)
DAS, Rathindra, C.
Orange, CT 06477 (US)
(74)
Representative:
Chapman, Paul William, et al
Kilburn & Strode, 30 John Street
London WC1N 2DD
London WC1N 2DD (GB)
(54)
TRANSLOCATION SIGNAL FACILITATED NUCLEAR DELIVERY OF MACROMOLECULES