(19)

(11)

EP 0 660 878 A1

(12)

(43) Date of publication: 05.07.1995 Bulletin 1995/27 (21) Application number: 93917823.0 (22) Date of filing: 19.08.1993

(51) International Patent Classification (IPC):  C12Q 1/ 68( . ) (86) International application number: PCT/FI1993/000329 (87) International publication number: WO 1994/004707 (03.03.1994 Gazette 1994/06)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI NL PT SE (30) Priority: 19.08.1992 FI 19920003719 (71) Applicants: TUOMILEHTO, Jaakko FIN-00920 Helsinki (FI) TUOMILEHTO-WOLF, Eva FIN-00920 Helsinki (FI)	(72) Inventors: TUOMILEHTO, Jaakko FIN-00920 Helsinki (FI) TUOMILEHTO-WOLF, Eva FIN-00920 Helsinki (FI) (74) Representative: Bunke, Holger, Dr.rer.nat. Dipl.-Chem.  Prinz & Partner Manzingerweg 7 D-81241 München D-81241 München (DE)