(19)

(11)

EP 0 661 962 A1

(12)

(43) Date of publication: 12.07.1995 Bulletin 1995/28 (21) Application number: 93921663.0 (22) Date of filing: 22.09.1993

(51) International Patent Classification (IPC):  A61K 8/ 34( . ) A61K 8/ 81( . ) A61Q 5/ 02( . ) A61K 8/ 73( . ) A61K 8/ 891( . ) A61Q 5/ 12( . ) (86) International application number: PCT/US1993/008823 (87) International publication number: WO 1994/006403 (31.03.1994 Gazette 1994/08)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE (30) Priority: 22.09.1992 US 19920948517 13.09.1993 US 19930118412 (71) Applicant: Colgate-Palmolive Company New York, N.Y. 10022-7499 (US)	(72) Inventors: REICH, Charles Highland Park, NJ (US) CHENG, Wei-Ming Piscataway, NJ (US) ROBBINS, Clarence R. Martinsville, NJ (US) PATEL, Amrit Dayton, NJ (US) (74) Representative: UEXKÜLL & STOLBERG  Patentanwälte Beselerstrasse 4 D-22607 Hamburg D-22607 Hamburg (DE)